Anti-Manic Agents

Subject: Mental Health (Theory)

Overview

Mood stabilizers are another name for antimanic medications. Bipolar affective disorder is treated with mood stabilizers. Frequently prescribed lithium is regarded as the best treatment for the manic stage of bipolar illnesses. Lithium is quickly absorbed from the digestive system. Hours pass before plasma reaches its peak. In around 8 hours, the absorption is essentially complete. Acute manic episodes, prevention of bipolar and unipolar mood disorders, schizoaffective disorder, cyclothymia, etc. are among the indications for lithium use. Patients using lithium frequently experience polyuria, perhaps as a result of lithium blocking the effects of the antidiuretic hormone on the renal tube. Make sure the patient doesn't engage in any alertness-demanding tasks until this response has calmed. Inform your doctor so that they can adjust your beta blocker propranolol dosage to lessen this side effect.

Anti-Manic Agents

Mood stabilizers are another name for antimanic medications. Bipolar affective disorder is treated with mood stabilizers. Frequently prescribed lithium is regarded as the best treatment for the manic stage of bipolar illnesses. Lithium is quickly absorbed from the digestive system. Hours pass before plasma reaches its peak. In around 8 hours, the absorption is essentially complete. The kidneys are mostly used for elimination. Lithium is absorbed in the proximal tubules and is affected by sodium balance. When sodium levels are low, lithium poisoning can develop quickly.

Lithium Indication

  • Acute mania
  • Bipolar and unipolar mood disorder prevention.
  • Schizoaffective illness.
  • Cyclothymia.

Contraindication/Precaution

  • People who are extremely sensitive to the medicine.
  • Severe kidney or cardiovascular problems.
  • Really dehydrated.
  • Depletion of sodium or using diuretics
  • Brain injury
  • Throughout the first trimester of pregnancy and when nursing.

Mechanism of Action

Antimanic drugs' precise biochemical mode of action is unknown. Lithium modifies the reuptake of biogenic amines in the brain and changes sodium metabolism in nerve and muscle cells, lowering body levels and reducing hyperactivity. It might prevent sensitive dopamine receptors from developing in persons with bipolar disorder's CNS. Both antimanic and depressive effects can be attributed to lithium. In order to control mood swings and impulse along nerve cells, lithium also aids in maintaining the sodium content in the brain.

Daily Dose

  • Acute mania
    • 2-4 divided doses of 1800 to 2400 mg are administered.
  • Maintenance
    • 300 to 1200 mg

Nursing Intervention

Side Effect

  • Fatigue, vertigo, and headache.
  • Mouth dryness thirst
  • Nausea/vomiting due to gastrointestinal (GI) distress.
  • Small hand trembles.
  • Arrhythmias, hypotension, and irregular heartbeat.
  • Gaining weight
  • Polyuria and thirst from dehydration Patients using lithium frequently experience polyuria, perhaps as a result of lithium blocking the effects of the antidiuretic hormone on the renal tube.

Nursing Implication

  • Make sure the patient doesn't engage in any alertness-demanding tasks until this response has calmed.
  • Give the patient ice, sugar-free chocolates, and regular water sips.
  • Give the patient instructions to consume 10 to 12 glasses of water each day.
  • Maintaining strict oral hygiene is crucial.
  • To reduce GI discomfort, take medicine dosages with meals. Dividing daily dosage may also assist.
  • Assure them that the signs and symptoms will pass.
  • Inform your doctor so that they can adjust your beta blocker propranolol dosage to lessen this side effect.
  • Keep an eye on your vital signs frequently (bid or tid).
  • Discuss with a doctor prescribing a lower dosage of medication.
  • Keep an eye on your weight, daily consumption, and output.
  • Daily check on skin turgor.
  • Report any production that exceeds 3000 ml every 24 hours.
  • Inform the patient about a low-calorie diet.
  • Stress the significance of keeping a sufficient salt intake.
  • Weight record per week.
Things to remember
  • Mood stabilizers are another name for antimanic medications. Bipolar affective disorder is treated with mood stabilizers.
  • Frequently prescribed lithium is regarded as the best treatment for the manic stage of bipolar illnesses.
  • Lithium is quickly absorbed from the digestive system.
  • Hours pass before plasma reaches its peak.
  • In around 8 hours, the absorption is essentially complete.
  • Acute manic episodes, prevention of bipolar and unipolar mood disorders, schizoaffective disorder, cyclothymia, etc. are among the indications for lithium use.
  • Patients using lithium frequently experience polyuria, perhaps as a result of lithium blocking the effects of the antidiuretic hormone on the renal tube.
  • Make sure the patient doesn't engage in any alertness-demanding tasks until this response has calmed.
  • Inform your doctor so that they can adjust your beta blocker propranolol dosage to lessen this side effect.
Questions and Answers

Mood stabilizers are another name for antimanic medications. Bipolar affective disorder is treated with mood stabilizers. Frequently prescribed lithium is regarded as the best treatment for the manic stage of bipolar disorders.

Lithium Indication

  • Severe mania
  • Bipolar and unipolar mood disorder prevention
  • Psychopathic disorder
  • Cyclothymia

Contraindication/Precaution

  • People who are extremely sensitive to the medicine.
  • Severe kidney or cardiovascular problems.
  • Really dehydrated.
  • Depletion of sodium or using diuretics
  • Brain injury
  • During a pregnant woman's first trimester and while nursing.
  • Make sure the patient doesn't engage in any alertness-demanding tasks until this response has calmed.
  • Give the patient ice, sugar-free chocolates, and regular water sips.
  • Give the patient instructions to consume 10 to 12 glasses of water each day.
  • Maintaining strict oral hygiene is crucial.
  • To reduce GI discomfort, take medicine dosages with meals. Dividing daily dosage may also assist.
  • Assure them that the signs and symptoms will pass.
  • Inform your doctor so that they can adjust your beta blocker propranolol dosage to lessen this side effect.
  • Keep an eye on your vital signs frequently (bid or tid).
  • Discuss with a doctor prescribing a lower dosage of medication.
  • Keep an eye on your weight, daily consumption, and output.
  • Daily check on skin turgor.
  • Report any production that exceeds 3000 ml every 24 hours.
  • Inform the patient about a low-calorie diet.
  • Stress the significance of keeping a sufficient salt intake.
  • Weight record per week.

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