Puerperal Sepsis

Subject: Midwifery III (Theory)

Overview

Puerperal sepsis is a serious or life-threatening illness that occurs during puerperium. Puerperium abnormalities are more common in the second and third weeks, but they can arise as early as 6 weeks after the puerperium stage. Puerperal sepsis is a genital tract infection that occurs during the first 6 weeks of pregnancy. Unless shown differently, puerperal pyrexia is thought to be caused by a genital tract infection. Puerperal pyrexia is defined as a spike in the temperature of 100°F or higher on two distinct occasions 24 hours apart within the first days after delivery. It is a visible ailment in several places of the world. Puerperal pyrexia is caused by Puerperal sepsis, UTI, breast problems, infection of laboratory wound, intercurrent infections, thrombophlebitis, tuberculosis, and unknown reasons.

Puerperal sepsis is an infection of the genital tract during the first 6 weeks of pregnancy. It rises as a result of an organism's invasion, incubation, and multiplication and hence does not generally occur until 24 hours or more following delivery. Unless shown differently, puerperal pyrexia is thought to be caused by genital tract infection.

Puerperal pyrexia

Puerperal pyrexia is defined as an increase in temperature of 100°F or more on two distinct times within 24 hours of delivery. In some regions of the world, it is a noticeable ailment.

Puerperal pyrexia can be caused by Puerperal sepsis, UTI, breast problems, infection of laboratory wound, intercurrent infections, thrombophlebitis, tuberculosis, or an unknown cause.

Causes

Infecting organism

The organisms responsible for Puerperal sepsis are the following :

  1. Aerobic: Staphylococcus pathogens, escherichia coli, klebsiella, pseudomonas, non-hemolytic streptococcus, Staphylococcus aureus.
  2. Anaerobic: Anaerobic streptococcus, bactericides, clostridium welchii, clostridium tetani.

    Source of infections
    Endogenous sources: This is frequently caused by an organism that is already present in the patient's vagina and intestine. In normal conditions, the bacteria are non-pathogenic. If the birth canal is lacerated, it can become virulent and pathogenic.
    Exogenous: Organisms from the patient's attendant's respiratory tract and septic foci The main source of infection is dust in the ward's air, which can come through a blanket, sheet, or other item. The majority of hospital personnel have Straphylococcus and streptococci in their respiratory tracts and will easily infect their patients if proper precautions are not implemented.
     
  3. Autogenous: In this course, the patient's respiratory tract is the most common source of infection; however, septic foci may also be a source of infection.
  4. The predisposing factor

The pathogenicity of the vaginal flora may be influenced by certain factors;

  1. Condition that reduces resistance—general or local.
  2. The organisms' pathogenicity increased as a result of the conditions encouraging proliferation.
  3. External organisms are introduced.
  4. Resistance to antibiotics and chemotherapy is becoming more common.

Antepartum factors

  • Anemia and malnutrition
  • Pre-eclampsia
  • Premature membrane rupture very devastating disease sexual intercourse in late pregnancy

Intrapartum factors

  • Introgression of sepsis into the upper vaginal tract during the internal inspection, particularly after membrane rupture or during manipulative delivery.
  • During labor, there is dehydration and ketoacidosis.
    a violent surgical delivery
  • APH and PPH hemorrhaged retained placental tissue and membrane.
  • Long-term Previa: the placental location is close to the vagina.
  • Extensive perineum, vaginal, and cervix lacerations are substantial risk factors, especially if the laceration is not repaired on time.

Types of Puerperal Sepsis

  1. Localized infection
    • There is a small temperature rise, nonspecific malaise, or a headache.
    • The local wound gets puffy and red.
    • Tachycardia, lower abdominal pain, and soreness
    • Pus may occur, causing the wound to be disrupted.
  2. Uterine infection
    • There is fluctuating pyrexia with a corresponding rise in pulse rate.
    • Lochia discharge becomes obnoxious, abundant, and frequently red.
    • Subinvoluted, sensitive, and softer than typical uterine.
    • In severe cases, the start is abrupt, with a rapid rise in temperature,
    • typically accompanied by chills and rigors.
  3. Spread of infection
    • Spread of the femoral vein, iliac vein, inferior vena cava, fallopian tube, calf muscle thrombophlebitis, and pain on dorsiflexion
    • Peritonitis\Septicemia

Causes

  • This could happen within 48 hours of delivery.
  • High temperature, confusion, abdominal pain, which may or may not be absent, and joint pain make the patient appear very unwell and toxic.

Prevention

Puerperal sepsis can be avoided to a large extent. Certain precautions should be taken before, during, and after labor.

  1. Antenatal
    • Detect and eliminate septic foci, particularly those found in the teeth, gums, tonsils, middle ears, and so on.
    • Maintain and enhance the patient's health status, particularly to raise Hb levels, prevent eclampsia, and treat any anomalies as soon as possible.
    • Vaginal examinations should be kept to a minimum throughout pregnancy, especially in the later months, and should be performed with proper surgical asepsis.
    • Intercourse should be avoided during the last two months to avoid the spread of germs such as streptococcus.
    • The patient should avoid contact with others who have contagious disorders.
    • Personal hygiene should be maintained by the patient.
  2. Intra natal
    • To prevent infection, the nurse, doctor, and other workers entering the labor room should wear a mask, gown, and cap.
    • The delivery should be carried out with complete surgical asepsis.
    • The membrane should be preserved for as long as possible.
    • Well managed at every stage of the labor process, which eliminates the danger of infection.
    • To avoid tiredness in the mother, avoid protracted labor.
    • Traumatic vaginal delivery should be avoided, but if necessary, thorough surgical asepsis should be maintained.
    • In the labor room, dust should be avoided.
    • Laceration of the vaginal tract should be healed swiftly and methodically while maintaining perfect homeostasis and performing all necessary aseptic precautions.
    • Excessive blood loss during birth should be replenished as soon as possible with a blood transfusion to increase overall body resistance.
  3. Postnatal period
    • Aseptic measures should be observed for at least one week after delivery until the open wound in the uterus and any genital tract injuries have healed.
    • While providing perineal care, the nurse should use aseptic precautions and wear a mask.
    • Limit the number of visits to the ward.
    • To avoid lochia from decomposing and becoming foul on the pad, use sterilized sanitary pads and change them frequently.
    • After each urination and defecation, clean the vulval area with an antiseptic solution.
    • Isolation, as well as barrier nursing techniques, are critical for infected patients and newborns.
    • It is recommended that you refrain from having sexual relations for at least 4-to 6 weeks after giving birth.

Management

  • As soon as the patient is diagnosed with puerperal sepsis, she should be isolated and cared for in a separate room.
  • To assist in lowering the temperature, use a tepid sponge.
  • Items used to care for the mother should be stored separately.
  • Determine the source of the fever and treat it accordingly.
  • While caring for the mother, midwives must wear a gown and a mask.
  • The patient's diet or food must be nutritious and easily digestible.
  • Encourage adequate fluid consumption.
  • Maintain the patient's personal hygiene by giving perineal care and encouraging oral hygiene.
  • Encourage the mother to empty her bladder on a regular basis.
  • An intake and output chart should be kept.
  • Keep track of vital signs.
  • Fundal height and lochia should be measured on a daily basis.
  • Inject Ampicillin 2 gm IV every 6 hours or Cefotaxim 1 gram every 8 hours.
  • Gentamycin 5mg/kg/body weight injected every 12 hours.
  • Metronidazole 500mg/8 hourly IV inj.
  • The treatment should be continued for at least 10 days after the infection has been controlled.
Things to remember
  • Major disorder or life-threatening condition of puerperium is puerperal sepsis.
  • Abnormalities of puerperium most frequently occur in 2nd and 3rd weeks but may often be seen within 6 weeks of the puerperium stage.
  • Puerperal sepsis is a Puerperal infection of the genital tract during the first 6 weeks of delivery of abortion.
  • It rises as a result of invasion, incubation, and multiplication of an organism and does not therefore normally occur until 24 hours or more after delivery.
  • Puerperal pyrexia is considered to be due to genital tract infection unless proved otherwise.
  • A rise of temperature reaching 100°F or more on 2 separate occasions at 24 hours apart within the first days following delivery is called Puerperal pyrexia.
  • It is a noticeable condition in some parts of the world.
  • Puerperal pyrexia can be caused by Puerperal sepsis, UTI, breast problems, infection of laboratory wound, intercurrent infections, thrombophlebitis, TB, or an unknown cause.
Questions and Answers

Infection of the vaginal tract within the first six weeks after giving birth is known as puerperal sepsis. Since it results from an organism's invasion, incubation, and multiplication, it often doesn't rise until 24 hours or longer after delivery. Unless otherwise demonstrated, genital tract infection is thought to be the cause of puerperal pyrexia.

Pregnancy pyrexia

Puerperal pyrexia is defined as an increase in temperature of 100°F or higher on two separate occasions, separated by 24 hours, during the first few days after delivery. In some regions of the world, it is an obvious condition.

Management

  • General
    • The patient should be kept in a separate room and given isolation care as soon as puerperal sepsis is confirmed.
    • Use a sponge that is barely warm to assist lower the temperature.
    • Items used for maternal care should be stored separately.
    • Determine the reason of the fever and treat it appropriately.
    • While caring for the mother, midwives are required to wear a robe and mask.
    • The patient's diet or food must be wholesome and easily digestible.
    • Promote drinking enough water.
    • Maintain the patient's oral hygiene and provide perineal care to maintain personal hygiene.
    • Tell the mother to urinate frequently.
    • An intake and outflow chart needs to be kept up.
    • Watch your vital signs.
    • Daily checks of the lochia and fundal height are recommended.

Specific treatment

  • Send samples of your blood, urine, and vaginal discharge for a culture and sensitivity test, and then administer antibiotics based on the CS results. The two antibiotics that are used the most frequently are cefotaxime and ampicillin, respectively.
    • Gentamycin injection, 5mg/kg/body weight, every 12 hours.
    • IV injection of 500mg/8h metronidazole.
    • Once the infection has been under control for at least 10 days, the medication should be continued.
    • I and D of the perineal wound and abscess, respectively.

When thinking about the root of puerperal sepsis. The following things should be considered by the midwives.

  • The infecting organism.
  • The source of infection.
  • The predisposing factor.

The infecting organism

The following microbes are in charge of puerperal sepsis:

  • Aerobic: non-hemolytic streptococcus, klebsiella, pseudomonas, Straphylococcus phogens, and Straphylococcus aureus.
  • Clostridium welchii, bacteriodes, and clostridium tetani are examples of anaerobic organisms.

The source of infections

  • Endogenous sources: This typically comes from bacteria that are already living in the patient's intestine and vagina. In healthy conditions, the organism is not harmful. If there is a laceration in the birth canal, they could become pathogenic and virulent.
  • Exogenous: Microorganisms from the patient's attendant's septic foci and respiratory tract. The primary cause of infection is dust from blankets, sheets, and other items that are in the ward's air. If proper precautions are not taken, the majority of hospital staff members will easily infect their patients with strep and streptococci from their respiratory tracts.
  • Autogenous: In this case, the patient's respiratory system is typically where the infection comes from, though septic foci can also be a source of infection.

The predisposing factor

There are few factors that may affect how harmful the vaginal flora is;

  • Low resistance conditions, either global or local.
  • Conditions that encouraged growth and boosted the germs' pathogenicity.
  • Introduction of foreign organisms.
  • Increased incidence of bacteria resistant to chemotherapy and antibiotics.

Antepartum factors

  • Anemia and undernutrition.
  • Pre-eclampsia,
  • An early membrane rupture, 
  • A persistent, incapacitating sickness
  • Having sex in the latter stages of pregnancy.
  • Intrapartum influences
  • The introduction of sepsis into the upper vaginal tract when undergoing an internal examination, particularly following membrane rupture or during manipulative childbirth.
  • During labor, dehydration and ketoacidosis.
  • Traumatic surgical delivery
  • Retained fragments of placental tissue and membrane due to bleeding (APH and PPH).
  • Extended previa: vaginal vicinity of the placental location.
  • Significant perineum, vaginal, and cervix lacerations are significant predisposing factors, particularly if the laceration is not healed in a timely manner.

Types of puerperal sepsis

  • Localized infection
    • A mild increase in body temperature, a widespread illness, or a headache are present.
    • The nearby wound turns crimson and swells.
    • Tachycardia, lower abdominal pain, and tenderness.
    • Pus formation could cause the wound to become infected.
  • Uterine infection
    • There is pyrexia of varying severity and a corresponding rise in heart rate.
    • Lochia discharge turns foul, profuse, and frequently red.
    • The uterus is more sensitive, subinvoluted, and delicate than typical.
    • In severe cases, the onset is sudden, the temperature rises sharply, and chills and rigors are frequently present.
  • Spread of infection
    • Symptoms include pain with dorsiflexion as well as the spread of the femoral vein, iliac vein, inferior vena cava, fallopian tube, and thrombophlebitis of the calf muscle.
      • Peritonitis
      • Septicemia
    • Within 48 hours of delivery, this might happen.
    • A fever
    • Delirium
    • Abdominal discomfort is typically absent.
    • Discomfort in joints
    • Patient appears to be poisonous and very unwell.

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